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Heartburn

Eating spicy foods, such as pizza, may cause a person to feel heartburn. Although the name may imply the heart, heartburn has nothing to do with the heart itself. Heartburn is pain felt in the chest by a burning sensation in the esophagus.

Heartburn
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Health News

Apply to Become a National Youth Sports Strategy Champion!

The National Youth Sports Strategy’s vision is that one day, all youth will have the opportunity, motivation, and access to play sports. To realize this vision, we need the help of partners from across the youth sports landscape. Th. See on Source

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01/02/2023

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February National Health Observances: Heart Health, Teen Dating, Girls & Women in Sports, and Black HIV/AIDS Awareness

Each month we feature select National Health Observances (NHOs) that highlight issues affecting health across the nation. This month we are raising awareness about heart health, teen dating violence, girls & women in sports, and Bla. See on Source

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31/01/2023

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Establishing Equitable Resilience Requires Shared Stewardship

Health and Well-Being Matter is the monthly blog of the Director of the Office of Disease Prevention and Health Promotion. … Read post   . See on Source

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30/01/2023

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Austin Public Health Launches Social and Digital Ad Campaign

Move Your Way® is the promotional campaign for the second edition of the Physical Activity Guidelines for Americans. Over the past 3 years, ODPHP has worked with communities across the country to implement the campaign. From 2019 to. See on Source

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25/01/2023

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Announcing the 2025 Dietary Guidelines Advisory Committee!

The U.S. Department of Health and Human Services (HHS) and the U.S. Department of Agriculture (USDA) are excited to announce the members of the 2025 Dietary Guidelines Advisory Committee! The Committee will review the current body o. See on Source

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19/01/2023

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Healthy People, Healthy Hearts: Healthy People 2030 and Cardiovascular Health

On December 6, 2022 the Office of Disease Prevention and Health Promotion (ODPHP) and the National Center for Health Statistics (NCHS) hosted the fourth installment of the Healthy People 2030 Webinar Series, Healthy People, Healthy . See on Source

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17/01/2023

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Firearm Safety and Public Health

Health and Well-Being Matter is the monthly blog of the Director of the Office of Disease Prevention and Health Promotion. … Read post   . See on Source

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23/12/2022

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Use Our New Speaker Request Form!

Did you know you can request ODPHP staff and members of the President’s Council on Sports, Fitness & Nutrition (PCSFN) as speakers at your events? And with our new Speaker Request Form, it’s easier than ever! … Read post   . See on Source

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19/12/2022

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Learn How to Use Healthy People 2030 Evidence-Based Resources in Your Work

Healthy People 2030 sets measurable objectives to improve the health and well-being of people across the United States — and provides tools and materials to help individuals and organizations achieve them. These tools include eviden. See on Source

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08/12/2022

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Akron-Summit County Public Library and Healthy People: Prioritizing Educational Opportunities for Community Members

This post is part of Healthy People 2020 in Review, a blog series highlighting how organizations across the nation are addressing social determinants of health — and how their efforts have helped us make progress toward Healthy Peop. See on Source

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05/12/2022

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UN News - Health

Global perspective, human stories

WHO launches bid to tackle inequalities behind global breast cancer threat

A UN-led global initiative to tackle breast cancer could save 2.5 million lives by 2040, the World Health Organization (WHO) said on Friday, just ahead of World Cancer Day.. See on Source

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03/02/2023

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Fake medicines kill almost 500,000 sub-Saharan Africans a year: UNODC report

Trafficked medical products kill almost half a million sub-Saharan Africans every year, and action is needed to stem the flow, the United Nations Office on Drugs and Crime (UNODC) states in its new threat assessment report.. See on Source

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01/02/2023

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African leaders commit to end AIDS among children by 2030

UN agencies have welcomed a pledge by 12 African countries to end AIDS in children by 2030, announced on Wednesday at a meeting in Dar Es Salaam, Tanzania. . See on Source

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01/02/2023

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Tedros: COVID-19 remains an international health threat

The head of the UN health agency, Tedros Adhanom Ghebreyesus, said on Monday that COVID-19 is still a global health threat and that now is not the time to declare the pandemic over.. See on Source

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30/01/2023

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WHO calls for more action to end ‘cycles of poverty and stigma’ related to tropical diseases

More countries have worked to eliminate dengue, leprosy and other neglected tropical diseases (NTDs) over the past decade, but greater efforts and investment are needed in the face of pandemic-related disruptions, the World Health Organization (WHO) said . See on Source

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30/01/2023

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WHO calls for action to totally eliminate trans fat, ‘a toxic chemical that kills’

Despite recent progress towards eliminating trans fat from food, some five billion people remain unprotected from its harmful impacts, thus increasing their risk of heart disease and death, the World Health Organization (WHO) said on Monday. . See on Source

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23/01/2023

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$2.54 billion needed to tackle unprecedented health needs in 2023: WHO  

Two-and-a-half billion dollars: that’s how much funding the UN World Health Organization (WHO) will need across its operations this year, it said on Monday, to help a record number of people facing disease and starvation. . See on Source

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23/01/2023

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‘We are not afraid’: Indigenous Brazilian women stand up to gender violence

Women from Brazil’s indigenous communities are particularly vulnerable to gender-based violence, but UN-backed initiatives, and a change in the law, are encouraging them to seek protection.. See on Source

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21/01/2023

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COVID-19: China ‘making enormous progress’ to get every older adult vaccinated

China is “making enormous progress and effort” to get every older adult vaccinated against COVID-19, the UN health agency said on Friday, while also cautioning that it will take time to protect everyone.. See on Source

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20/01/2023

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Small island States to accelerate action on preventable diseases, mental health

Small Island Developing States (SIDS) are among countries that have the highest prevalence of non-communicable diseases (NCDs) and mental health risks in the world. Now, UN health agency WHO, is pledging to work more closely with them, to help save and im. See on Source

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18/01/2023

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WHO launches Council to develop TB vaccines, hoping to save millions of lives

The head of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, has unveiled plans to speed up the licensing and use of effective novel vaccines against tuberculosis (TB), the second leading infectious killer after COVID-19 and the 13th leadi. See on Source

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17/01/2023

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Nearly one billion served by healthcare facilities without reliable electricity

Although electricity is critical to healthcare provision, nearly a billion people in poorer countries - one-eighth of the global population - are served by health facilities that lack reliable supply, a UN-backed report launched on Saturday has revealed.. See on Source

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14/01/2023

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Motorbike ambulance saves mothers and babies in Kenya: UNFPA

The hardship being felt across the Horn of Africa by the worst drought in 40 years has left many women weak and malnourished. The UN agency dedicated to women’s sexual and reproductive health, UNPA, is helping save mothers’ lives in Kenya, through the don. See on Source

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12/01/2023

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Global food crisis putting millions of young lives at risk

Five UN agencies on Thursday called for urgent action to protect millions of malnourished children in the 15 countries hardest hit by the unprecedented food and nutrition crisis. . See on Source

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12/01/2023

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COVID-19: WHO highlights critical importance of sharing virus sequences

Although virus sequencing is vital to detect and track new variants in the COVID-19 pandemic, sharing this information must be stepped up globally, the head of the World Health Organization (WHO) said on Wednesday in Geneva. . See on Source

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11/01/2023

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Uganda declares end of Ebola virus outbreak

In Uganda, a deadly outbreak of Ebola virus has been stopped in its tracks and declared officially over, the UN World Health Organization (WHO) said on Wednesday.  . See on Source

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11/01/2023

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COVID in Europe: China’s surge not a cause for concern ‘at this time’ says WHO, as XBB.1.5 virus spreads

The ongoing COVID-19 surge in China is not expected to “significantly impact” the European region, UN health experts said on Tuesday.. See on Source

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10/01/2023

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Improve healthcare access to end ‘preventable tragedy’ of child mortality

A child or young person died every 4.4 seconds in 2021, and millions more could lose their lives by 2030 unless all women and children have access to adequate healthcare, two new detailed UN reports published on Monday have revealed. . See on Source

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09/01/2023

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Flexible work arrangements, a benefit to all – ILO report

Flexible working hours can advance economies and businesses while helping employees and families achieve a better work-life balance, according to a new report launched by the International Labour Organization (ILO) on Friday.. See on Source

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06/01/2023

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Featured News from HSPH

The potential fallout of ending the COVID-19 emergency

Ending the COVID-19 public health emergency, which the Biden administration plans to do in May 2023, could make it harder for some people—depending on their health insurance status—to access free vaccines and COVID-19 tests and treatments, according to ex... See on Source

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03/02/2023

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The latest on the coronavirus

Harvard Chan School experts offer comments and context about the coronavirus in a variety of media outlets.... See on Source

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02/02/2023

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Noise pollution can lead to sleep issues, chronic health problems

Noise pollution is a growing problem that can lead to sleep disruption and insomnia as well as chronic health conditions such as heart disease, cognitive impairment, depression, and anxiety, according to experts.... See on Source

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02/02/2023

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Dispelling nutrition myths

Ten experts recently told the New York Times which false ideas about nutrition they would like to dispel. One of those experts—Harvard T.H. Chan School of Public Health’s Sara Bleich—said that she’d like to dispel the myth that “Fresh fruits and vegetable... See on Source

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02/02/2023

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Telemedicine appears as effective as in-person care for opioid use disorder

Care for opioid use disorder can be effective whether provided in-person or via telemedicine, according to a new study co-authored by researchers from Harvard Chan School.... See on Source

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31/01/2023

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Pandemic impacted diets of Massachusetts adults experiencing food insecurity

Among Massachusetts adults with low incomes, those experiencing food insecurity reported greater disruptions in their diets during the early months of the COVID-19 pandemic than those not experiencing food insecurity.... See on Source

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27/01/2023

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Questions raised about PFAS in period products

Reusable “period underwear” that people use in place of traditional, disposable menstrual products may contain toxic compounds linked with long-term health risks.... See on Source

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27/01/2023

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Opinion: Three ways to promote health equity in Massachusetts

In the face of longstanding health disparities magnified during the COVID-19 pandemic, Massachusetts Gov. Maura Healey can take concrete steps to promote health equity, according to Harvard Chan School's Lumas Joseph Helaire.... See on Source

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26/01/2023

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Moderation key to alcohol’s potential health benefits

Evidence suggests that moderate alcohol consumption may provide some health benefits, but these must be weighed against potential risks.... See on Source

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26/01/2023

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Exposure to hormone-disrupting chemical mixtures common among office workers

Office workers in the U.S., the U.K., China, and India were exposed to complex mixtures of chemicals that can disrupt hormonal functions, according to a study that analyzed chemical traces picked up by silicone wristbands worn by the workers.... See on Source

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17/01/2023

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JPET current issue

Journal of Pharmacology and Experimental Therapeutics

Human Induced Pluripotent Stem Cell-Derived Keratinocyte-Like Cells for Research on Protease-Activated Receptor 2 in Nonhistaminergic Cascades of Atopic Dermatitis [Inflammation, Immunopharmacology, and Asthma]

Keratinocytes are the most abundant cells in the epidermis, and as part of the frontline immunologic defense system, keratinocytes function as a barrier to exogenous attacks. Protease-activated receptor 2 (PAR2) is expressed in human keratinocytes and ac... See on Source

jpet.aspetjournals.org

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07/02/2023

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Chlorogenic Acid Inhibits Epithelial-Mesenchymal Transition and Invasion of Breast Cancer by Down-Regulating LRP6 [Cellular and Molecular]

Epithelial-mesenchymal transition (EMT) is a crucial biologic process for breast cancer metastasis, and inhibition of EMT could be an effective approach to suppress metastatic potential of mammary cancer. High expression of low-density lipoprotein recept... See on Source

jpet.aspetjournals.org

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07/02/2023

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Effects of hsa-miR-9-3p and hsa-miR-9-5p on Topoisomerase II{beta} Expression in Human Leukemia K562 Cells with Acquired Resistance to Etoposide [Chemotherapy, Antibiotics, and Gene Therapy]

DNA topoisomerase IIα (TOP2α/170; 170 kDa) and topoisomerase IIβ (TOP2β/180; 180 kDa) are targets for a number of anticancer drugs, whose clinical efficacy is attenuated by chemoresistance. Our laboratory selected for an etoposide-r... See on Source

jpet.aspetjournals.org

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07/02/2023

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HM15912, a Novel Long-Acting Glucagon-Like Peptide-2 Analog, Improves Intestinal Growth and Absorption Capacity in a Male Rat Model of Short Bowel Syndrome [Gastrointestinal, Hepatic, Pulmonary, and Renal]

Extensive bowel resection caused by various diseases that affect the intestines, such as Crohn's disease, volvulus, and cancer, leads to short bowel syndrome (SBS). Teduglutide is the only approved glucagon-like peptide-2 (GLP-2) drug for SBS; however, i... See on Source

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07/02/2023

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Role of Hydrogen Sulfide in the Development of Colonic Hypomotility in a Diabetic Mouse Model Induced by Streptozocin [Gastrointestinal, Hepatic, Pulmonary, and Renal]

Hydrogen sulfide (H2S), a novel gasotransmitter, is involved in the regulation of gut motility. Alterations in the balance of H2S play an important role in the pathogenesis of diabetes. This study was conducted to investigate the role of H2S in the colon... See on Source

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07/02/2023

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The Effects of Indobufen on Micro-Inflammation and Peritoneal Transport Function in Patients Undergoing Continuous Ambulate Peritoneal Dialysis: A Prospective Randomized Controlled Study [Metabolism, Transport, and Pharmacogenetics]

Indobufen possesses anticoagulant and antithrombotic effects that can improve micro-inflammation and renal function. This study aimed to examine whether indobufen could improve the microinflammatory state in patients on continuous ambulatory peritoneal d... See on Source

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07/02/2023

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Novel Allosteric Modulator Southern Research Institute-32743 Reverses HIV-1 Transactivator of Transcription-Induced Increase in Dopamine Release in the Caudate Putamen of Inducible Transactivator of Transcription Transgenic Mice [Neuropharmacology]

Development of neurocognitive disorder in human immunodeficiency virus (HIV)-infected patients has been linked to dysregulation of dopamine by the HIV-1 transactivator of transcription (Tat) protein, a negative allosteric modulator of dopamine transporte... See on Source

jpet.aspetjournals.org

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07/02/2023

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Attenuation of Epileptogenesis and Cognitive Deficits by a Selective and Potent Kv7 Channel Opener in Rodent Models of Seizures [Neuropharmacology]

Targeting neuronal Kv7 channels by pharmacological activation has been proven to be an attractive therapeutic strategy for epilepsy. Here, we show that activation of Kv7 channels by an opener SCR2682 dose-dependently reduces seizure activity and severity... See on Source

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07/02/2023

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