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Healthy Articles

Heartburn

Eating spicy foods, such as pizza, may cause a person to feel heartburn. Although the name may imply the heart, heartburn has nothing to do with the heart itself. Heartburn is pain felt in the chest by a burning sensation in the esophagus.

Heartburn
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Health News

Join the Move Your Way Campaign LinkedIn Community!

The Move Your Way® campaign — the promotional campaign for the second edition of the Physical Activity Guidelines for Americans — helps health professionals encourage people to be active where they live, learn, work, and play. ODPHP. See on Source

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29/09/2023

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Check-out Healthy People’s New "5 Things to Know About Health Equity" Video

Healthy People just released a new 5 Things to Know About Health Equity video! Achieving health equity requires valuing everyone equally with focused and ongoing societal efforts to address avoidable inequalities, historical and con. See on Source

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28/09/2023

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Let’s Get Educated About Sickle Cell Disease

By Alexis A. Thompson, MD, MPH, Chief of the Division of Hematology at Children’s Hospital of Philadelphia … Read post   . See on Source

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27/09/2023

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October National Health Observances: Health Literacy, Breast Cancer, Youth Sports, and HIV/AIDS Awareness

Each month, we highlight National Health Observances (NHOs) that align with our mission to improve health across the United States. In October, we’re raising awareness about health literacy, breast cancer, the benefits of youth spor. See on Source

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25/09/2023

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Healthy People 2030 Launches New Healthy People in States and Territories Page

Healthy People 2030 is pleased to announce the publication of a new Healthy People in States and Territories web page. This new page provides: … Read post   . See on Source

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21/09/2023

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ICYMI: 2025 Dietary Guidelines Advisory Committee Held Third Meeting, Heard Public Oral Comments

Rockville, Md. – ICYMI: Last week, on September 12 and 13, the 2025 Dietary Guidelines Advisory Committee convened in person for its third official meeting. The meeting was livestreamed. … Read post   . See on Source

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20/09/2023

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Check Out Our New Resource on Social Determinants of Health and Older Adults

September is Healthy Aging Month — and to celebrate, ODPHP is launching the new Social Determinants of Health and Older Adults resource. … Read post   . See on Source

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18/09/2023

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Register Today for the next Healthy People 2030 Webinar “Injury and Violence Prevention Strategies for the LGBTQ+ Community”

Space is still available for the Office of Disease Prevention and Health Promotion's (ODPHP) next webinar: Injury and Violence Prevention Strategies for the LGBTQ+ Community. This webinar will take place on Tuesday, September 19 fro. See on Source

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11/09/2023

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There’s Still Time to Register for the Third Meeting of the 2025-2030 Dietary Guidelines Advisory Committee

On September 12 and 13, HHS and USDA will host the third meeting of the 2025 Dietary Guidelines Advisory Committee. The Committee is tasked with reviewing the current body of science on key nutrition and public health topics and dev. See on Source

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11/09/2023

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Third Meeting of the 2025 Dietary Guidelines Advisory Committee to Convene September 12 - 13, 2023

On September 12 and 13, HHS and USDA will host the third meeting of the 2025 Dietary Guidelines Advisory Committee. The Committee is tasked with reviewing the current body of science on key nutrition and public health topics and dev. See on Source

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05/09/2023

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UN News - Health

Global perspective, human stories

Sudan: WHO supports battle against cholera in the east

The World Health Organization (WHO) is scaling up support in Sudan, where authorities have declared a cholera outbreak in Gedaref state amid the ongoing brutal conflict between opposing militaries. . See on Source

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29/09/2023

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Ban smoking and vaping in schools worldwide urges WHO

Young people continue to be “relentlessly” targeted with tobacco and nicotine products, the World Health Organization (WHO) warned on Tuesday, in a call to ban smoking and vaping “whether sitting in class, playing games outside or waiting at the school bu. See on Source

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26/09/2023

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New global action pledge to end TB by 2030

Applause rang out in one of the main conference rooms at UN headquarters on Friday as world leaders, civil society representatives and other stakeholders approved a declaration to advance efforts to end tuberculosis (TB) by 2030. . See on Source

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22/09/2023

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Healthcare: Lack of universal coverage, ‘human rights tragedy on a massive scale’

World leaders on Thursday agreed to boost efforts to provide universal health coverage for all by 2030.. See on Source

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21/09/2023

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World News in Brief: Peace day, high seas treaty, Palestinian displacement rises, polio in Ukraine

Peace requires strong mobilization for human rights, sustainable development and the environment, UN Secretary-General António Guterres said on the International Day of Peace observed on Thursday.. See on Source

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21/09/2023

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Health chief hails ‘historic milestone’ in race to avert next pandemic

UN Member States on Wednesday pledged to prevent a repeat of the devastating health and socioeconomic crises caused by COVID-19 and shore up the world’s ability to head off another pandemic.. See on Source

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20/09/2023

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Global leaders discuss healthier future for all: Top 5 fast facts

Some 4.5 billion people, more than half the global population, do not have enough access to essential health services, an issue that world leaders and ministers will tackle at a series of high-level meetings at the UN this week.. See on Source

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20/09/2023

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‘Radical reorientation’ needed as half of humanity lacks basic health coverage

Over 4.5 billion people worldwide lack coverage for essential health services the UN health agency said on Monday, underscoring the need for stronger political commitment and increased government investment.. See on Source

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18/09/2023

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UNGA78: UN chief brushes off key leaders' absence, says delivery paramount

With several high-profile world leaders opting out of the UN General Assembly’s annual opening session next week, Secretary-General António Guterres has said that he cares less about who comes to New York and more about what gets done, especially to reviv. See on Source

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16/09/2023

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Preserving dignity, public health: Managing deceased bodies during crises

The UN World Health Organization (WHO) on Friday joined with the Red Cross and Red Crescent Societies, to underline the critical importance of preserving the dignity of the dead in the wake of recent natural disasters in Libya and Morocco.. See on Source

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15/09/2023

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Rights expert appeals for action to tackle elder abuse

A UN-appointed human rights expert on Friday called for urgent action and better data to stamp out the widespread problem of elder abuse. . See on Source

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15/09/2023

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‘Act together’ for clean air, Guterres urges

Marking the International Day of Clean Air for Blue Skies on Thursday, UN Secretary-General António Guterres issued a powerful call for increased international cooperation to address the “global emergency” of worsening air pollution. . See on Source

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06/09/2023

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'Climate breakdown' alert as air quality dips during heatwaves: UN chief

Amplified by wildfires and desert dust fanned by climate change, more frequent heatwaves are leading to a sharp drop in air quality and human health, the World Meteorological Organization (WMO) said in a new report on Wednesday.. See on Source

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06/09/2023

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Yemen: Alarming surge in measles and rubella cases, reports WHO

The UN World Health Organization (WHO) issued a stark warning on Thursday over rising cases of measles and rubella among children in Yemen, as a vaccination campaign there faces cutbacks due to insufficient funding.. See on Source

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31/08/2023

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Refusal to waive IP rights for COVID-19 vaccines violates human rights: Experts

UN rights experts called on States in the global North on Thursday to forgo intellectual property rights on COVID-19 vaccines and treatments in the name of human rights. . See on Source

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31/08/2023

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With COVID-19 ‘here to stay’, new tools essential to continue fight: Tedros

The World Health Organization (WHO) on Tuesday announced an expanded partnership to improve access to COVID-19 technology, knowledge and clinical data, stressing the fight against the virus must continue.. See on Source

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29/08/2023

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More than two million children displaced by Sudan war: UNICEF

The conflict in Sudan has uprooted more than two million children – an average of more than 700 newly displaced every hour, the UN Children’s Fund (UNICEF) reported on Thursday. . See on Source

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24/08/2023

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UNFPA reveals winners of AccessAbility innovation challenge

Four organizations working with young people with disabilities are the winners of the first AccessAbility innovation challenge held by the United Nations sexual and reproductive health agency, UNFPA. . See on Source

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22/08/2023

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From Death Valley to the Swiss Alps, extreme weather records hit new heights

As sweltering conditions continue to grip large parts of Europe, temperatures have “reached new heights” in Switzerland, the UN World Meteorological Organization (WMO) warned on Tuesday.. See on Source

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22/08/2023

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Featured News from HSPH

As federal support for free school meals drops, kids’ stigma may increase

With the end of pandemic-era federal support that provided free school breakfasts and lunches for all, experts worry that kids who continue to need free meals will face increasing stigma.... See on Source

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28/09/2023

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Microplastics may disproportionately harm vulnerable communities

Harvard Chan School research scientist Mary Johnson says that vulnerable communities are particularly impacted by microplastics.... See on Source

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28/09/2023

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Exploring rising cancer rates in younger people

Cancer rates are increasing in people below the age of 50, a trend that could be driven by obesity and other factors, according to experts.... See on Source

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27/09/2023

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COVID update: tests, business readiness, ‘new normal’

Although COVID cases have ticked up, there is also good news: Old COVID tests may still be good; businesses should know how to pivot if infections keep climbing; and overall COVID conditions aren't nearly as bad as they were even a year ago.... See on Source

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22/09/2023

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Hair product safety could depend on where you live

Hair products sold in neighborhoods that are poorer or that have a higher percentage of residents of color were more likely to contain higher levels of hazardous chemicals than products sold in predominantly white and affluent areas, according to a study ... See on Source

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22/09/2023

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Reducing the risks of alcohol

The harmful effects of alcohol can be potentially lowered by prioritizing healthy habits, according to experts.... See on Source

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20/09/2023

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Harvard Chan faculty among those selected for Salata Institute climate grants

Two faculty members from Harvard Chan School are among 19 from across Harvard selected to receive support from the Salata Institute Seed Grant Program, launched in April to fund interdisciplinary research in climate and sustainability.... See on Source

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19/09/2023

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Examining the link between people’s sleep timing preferences, lifestyle, and diabetes

People who tend to stay up late have a higher risk of developing diabetes than those who rise early, a new study found.... See on Source

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19/09/2023

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More people traveling to Massachusetts for abortion care

In June 2022, the U.S. Supreme Court’s decision in the case of Dobbs v. Jackson overturned the constitutional right to abortion, leading many states to pass laws that restricted abortion access. In the months following the decision, more people traveled t... See on Source

hsph.harvard.edu

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19/09/2023

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How to practice mindful eating

“Mindful eating”—the practice of taking time to consciously experience, enjoy, and express gratitude for a meal—offers myriad health benefits, according to Harvard Chan School’s Lilian Cheung.... See on Source

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14/09/2023

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JPET current issue

Journal of Pharmacology and Experimental Therapeutics

Antinociceptive Effects of an Anti-CGRP Antibody in Rat Models of Colon-Bladder Cross-Organ Sensitization [Gastrointestinal, Hepatic, Pulmonary, and Renal]

Irritable bowel syndrome (IBS) and bladder pain syndrome/interstitial cystitis (BPS/IC) are comorbid visceral pain disorders seen commonly in women with unknown etiology and limited treatment options and can involve visceral organ cross-sensitization. Ca... See on Source

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30/09/2023

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KATP Channel Prodrugs Reduce Inflammatory and Neuropathic Hypersensitivity, Morphine-Induced Hypersensitivity, and Precipitated Withdrawal in Mice [Behavioral Pharmacology]

Previous studies show ATP-sensitive potassium (KATP) channel openers can reduce hypersensitivity associated with chronic pain models in rodents, and reduce morphine tolerance. Many agonists of KATP channels are not soluble in physiologically relevant veh... See on Source

jpet.aspetjournals.org

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30/09/2023

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Optimizing IFN Alpha Therapy against Myeloproliferative Neoplasms [Special Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine]

Myeloproliferative neoplasms (MPNs) are hematologic malignancies that result from acquired driver mutations in hematopoietic stem cells (HSCs), causing overproduction of blood cells and an increased risk of thrombohemorrhagic events. The most common MPN ... See on Source

jpet.aspetjournals.org

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30/09/2023

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Radiation in Combination with Immune Checkpoint Blockade and DNA Damage Response Inhibitors in Mice: Dosage Optimization in MC38 Syngeneic Tumors via Modelling and Simulation [Special Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine]

Clinical trials assessing the impact of radiotherapy (RT) in combination with DNA damage response pathway inhibitors (DDRis) and/or immune checkpoint blockade are currently ongoing. However, current methods for optimizing dosage and schedule are limited.... See on Source

jpet.aspetjournals.org

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30/09/2023

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A Mathematical Model to Investigate the Effects of Ceralasertib and Olaparib in Targeting the Cellular DNA Damage Response Pathway [Special Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine]

The ataxia-telangiectasia and Rad3-related (ATR) inhibitor ceralasertib and the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib have shown synergistic activity, in vitro, in the FaDu ATM-knockout cell line. It was found that combining these drugs ... See on Source

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30/09/2023

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Agent-Based Modelling Reveals the Role of the Tumor Microenvironment on the Short-Term Success of Combination Temozolomide/Immune Checkpoint Blockade to Treat Glioblastoma [Special Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine]

Glioblastoma is the most common and deadly primary brain tumor in adults. All glioblastoma patients receiving standard-of-care surgery-radiotherapy-chemotherapy (i.e., temozolomide (TMZ)) recur, with an average survival time of only 15 months. New approa... See on Source

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30/09/2023

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Mechanistically Weighted Metric to Predict In Vivo Antibody-Receptor Occupancy: An Analytical Approach [Special Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine]

In situ clinical measurement of receptor occupancy (RO) is challenging, particularly for solid tumors, necessitating the use of mathematical models that predict tumor receptor occupancy to guide dose decisions. A potency metric, average free tissue targe... See on Source

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30/09/2023

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Quantitative Systems Pharmacology and Machine Learning: A Match Made in Heaven or Hell? [Special Section on Quantitative Systems Pharmacology: A Foundation to Establish Precision Medicine-Minireview]

As pharmaceutical development moves from early-stage in vitro experimentation to later in vivo and subsequent clinical trials, data and knowledge are acquired across multiple time and length scales, from the subcellular to whole patient cohort scale. Rea... See on Source

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30/09/2023

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Role(s) of G3BPs in Human Pathogenesis [Minireview]

Ras-GTPase-activating protein (SH3 domain)-binding proteins (G3BP) are RNA binding proteins that play a critical role in stress granule (SG) formation. SGs protect critical mRNAs from various environmental stress conditions by regulating mRNA stability a... See on Source

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30/09/2023

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Role of ERK1/2 Signaling in Cinnabarinic Acid-Driven Stanniocalcin 2-Mediated Protection against Alcohol-Induced Apoptosis [Cellular and Molecular]

We have previously shown that a bona fide aryl hydrocarbon receptor (AhR) agonist, cinnabarinic acid (CA), protects against alcohol-induced hepatocyte apoptosis via activation of a novel AhR target gene, stanniocalcin 2 (Stc2). Stc2 translates to a secre... See on Source

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30/09/2023

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Mechanistic Model Describing the Time Course of Humoral Immunity Following Ad26.COV2.S Vaccination in Non-Human Primates [Drug Discovery and Translational Medicine]

Mechanistic modeling can be used to describe the time course of vaccine-induced humoral immunity and to identify key biologic drivers in antibody production. We used a six-compartment mechanistic model to describe a 20-week time course of humoral immune ... See on Source

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30/09/2023

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